Badanie epilepsji: Screening i diagnostyka
Investigating Epilepsy: Screening and Evaluation
W skrócie
Badanie dotyczy ludzi z diagnozą lub podejrzeniem epilepsji, którzy chcą wziąć udział w badaniach naukowych mających na celu lepsze zrozumienie drgawek i znalezienie najlepszych sposobów leczenia, szczególnie dla osób u których leki nie działają. Pacjenci przechodzą szereg badań: badania krwi, testy mózgu (EEG, MRI, MEG, PET), testy pamięci i myślenia, a czasem muszą być hospitalizowani przez kilka tygodni. Badanie przeznaczone jest dla dorosłych i dzieci od 8 roku życia z potwierdzoną lub podejrzewaną epilepsją.
Oryginalny opis (angielski)
Background:
Epilepsy affects about 1 percent of the U.S. population. Most people with epilepsy respond well to medicine, but some do not. Researchers want people who have diagnosed or suspected epilepsy to participate in ongoing studies. They want to learn more about clinical care for epilepsy. They want fellows and residents to learn more about the care of people with epilepsy.
Objectives:
To learn more about seizures and find ways to best treat people with drug-resistant epilepsy.
Eligibility:
Adults and children ages 8 years and older with diagnosed or suspected epilepsy
Design:
Participants will be screened with:
Physical exam
Medical history
Questionnaires
Participants will have many visits. They may be admitted to the hospital for several weeks. Their medication might be stopped or changed.
Participants will have many tests:
Blood and urine tests
EEG: Wires attached to the head with paste record brain waves. This may be videotaped.
Thinking and memory tests
MRI: Participants lie on a table that slides in and out of a tube. They perform simple tasks in the tube.
MEG: Participants lie on a table and place their head in a helmet to record brain waves.
PET scan: Participants lie on a table that slides into a machine. A small amount of radioactive dye is injected into their arm with an IV. For the IV, a small tube is inserted into the arm with a needle.
Participants will stay enrolled in this study if they join other epilepsy-related studies. They may be contacted at intervals for follow-up. Their participation will end if they have not been seen clinically for their epilepsy for 3 years.