Badanie korelacji między stygmatem, alienacją społeczną a jakością życia u osób z epilepsją

Abstract Background This study aims to investigate the current status of stigma and social alienation among people with epilepsy (PWE) and explore the correlation between stigma, social alienation, and quality of life in this population. Methods A total of 127 adult PWE who visited the neurology ward and epilepsy clinic of the First Affiliated Hospital of Harbin Medical University from January 1, 2022 to December 31, 2022, were enrolled. The general demographic and clinical characteristics questionnaire, Chinese version of the Kilifi Stigma Scale for Epilepsy (KSSE-C), General Social Alienation Scale (GAS), and Quality of Life Assessment Inventory for Epilepsy 31 (QOLIE-31) were used for data collection. Mini-Mental State Examination (MMSE) was applied for quality control (8 participants with cognitive impairment were excluded, with cut-off values adjusted by education level: illiterate ≤ 19 points, primary school ≤ 22 points, secondary school or above ≤ 26 points). This study was approved by the Ethics Committee of the First Affiliated Hospital of Harbin Medical University. All participants signed written informed consent forms. Data were analyzed using IBM SPSS Statistics for Windows, Version 26.0, including descriptive statistics, one-way analysis of variance (ANOVA) with effect size calculation, correlation analysis, univariate analysis, and multiple linear regression. Results Correlation analysis indicated that stigma was positively correlated with social alienation (r = 0.949, P