Czynniki wpływające na jakość życia młodzieży ze stwardnieniem padaczkowym: badanie przekrojowe z wykorzystaniem kwestionariusza QOLIE-AD-48
Factors associated with quality of life among adolescents with epilepsy: a cross-sectional study using the QOLIE-AD-48 questionnaire
W skrócie
Badanie oceniło jakość życia 109 nastolatków chorych na padaczkę za pomocą specjalnego kwestionariusza. Okazało się, że większość młodych pacjentów oceniła swoją jakość życia jako poślednią, a na wyniki wpłynęły takie czynniki jak płeć, częstość napadów padaczkowych, rodzaj stosowanego leczenia i przebyta operacja. Naukowcy zauważyli, że leczenie epilepsji powinno skupiać się nie tylko na zatrzymaniu napadów, ale również na ogólnym dobrostan psychicznym i społecznym nastolatków.
Oryginalny abstract (angielski)
UNLABELLED: Epilepsy is a chronic disorder that affects not only physical health but also the mental, social, and educational well-being of patients. This study aimed to evaluate the quality of life (QOL) of adolescent patients with epilepsy using the Quality of Life in Epilepsy Inventory for Adolescents (QOLIE-AD-48) and to identify factors associated with QOL. A cross-sectional observational study was conducted at a tertiary care teaching hospital among 109 adolescents (aged 12-18 years) with epilepsy. QOL was assessed using the QOLIE-AD-48 questionnaire. Associations between demographic and clinical variables were analyzed using descriptive statistics, independent-sample t-tests, one-way ANOVA with post hoc testing, Pearson correlation, linear regression, and chi-square analyses. Statistical significance was set at p ≤ 0.05. Most participants (54.13%) reported fair QOL, with a mean score of 55.24 ± 16.65. No significant associations were found between QOL scores and age, weight, systolic blood pressure, or diastolic blood pressure (p > 0.05). Independent-sample t-tests indicated that QOL scores were significantly influenced by gender, allergy history, and surgical history (all p < 0.05). One-way ANOVA demonstrated that, education level, seizure frequency in the past year and drug therapy significantly affected QOL scores (all p < 0.05). Chi-square analysis further identified significant associations between QOL categories and several demographic and clinical characteristics. CONCLUSION: The QOL of adolescents with epilepsy was significantly influenced by demographic and clinical variables. These findings emphasize that comprehensive epilepsy management must extend beyond seizure control to address broader aspects of patient well-being. WHAT IS KNOWN: • Quality of life in patients with epilepsy is influenced by seizure frequency, adverse effects of antiseizure medications, treatment regimen, educational attainment, and psychiatric comorbidities. • The QOLIE-AD-48 is a validated questionnaire specifically designed for adolescents, providing a comprehensive assessment across cognitive, emotional, social, behavioural, and epilepsy-related domains of quality of life. WHAT IS NEW: • This study examines the association of demographic, clinical, and treatment-related variables with quality of life in adolescents using complementary statistical approaches. • It highlights the combined influence of demographic, clinical, and treatment-related characteristics on quality of life in adolescents.